Gynecology & Obstetrics

Gynecology & Obstetrics
Open Access

ISSN: 2161-0932

Ebtesam M Kamal

Ebtesam M Kamal
Faculty of Medicine,

  • Research Article
    Effect of Uterine Flushing Leukemia Inhibitory Factor on Reproductive Outcome of Infertile Couple
    Author(s): Ebtesam M Kamal and Abeer M HafezEbtesam M Kamal and Abeer M Hafez

    Aim: To determine the role of Leukemia Inhibitory Factor (LIF) in predicting the reproductive outcome in infertile couple. Method of study: Uterine flushing and endometrialsamples were collected from infertile women during implantation window with stage I/II endometriosis (n=17), patients with idiopathic infertility (n=24), luteal phase defect (n=16), and fertile control (n=26). LIF was assessed in uterine flushings in all patients by ELISA. In endometrium, semiquantitative RT-PCR was performed for LIF mRNA expression. Reproductive outcome of all infertile women were recorderd. Results: 34.6% of patients included in the study got pregnant. LIF concentration had 96.5% sensitivity and 86.1% specificity at a cut-off point of 2.45 pg/ml for predicting the reproductive outcome. Conclusion: LIF.. View More»
    DOI: 10.4172/2161-0932.1000201

    Abstract PDF

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