ISSN: 2161-0940
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Dorothy A Frenz
Dorothy A Frenz
Research Professor
Department of Cell Biology and Anatomy
New York Medical College
Grasslands Reservation
USA
A primary focus of her research is the inner ear, which originates from a simple otic vesicle that ultimately gives rise to the complex organs of hearing and balance. Periotic mesenchyme surrounds the otic vesicle, giving origin to the cartilaginous otic capsule, which presages the formation of the endochondral bony capsule of the mature inner ear. Her research interests lie in the inductive tissue interactions that govern otic capsule morphogenesis, focusing on where in the embryonic inner ear molecular signals act, how they act, and the consequences of their inactivation. In addition, a recent interest focuses on the generation of brown adipose tissue from ectopic lineages in the mouse embryo.