Anatomy & Physiology: Current Research
Open Access

David Talbert

Publications

• Review Article
  Cerebral Venous Malformation as a Cause of Neonatal Intra-Ventricular Haemorrhage and Unexplained Infant Subdural Haemorrhage
  Author(s): David TalbertDavid Talbert
  
  An Intra-ventricular Haemorrhage (IVH) is a bleeding into the brain?s ventricular system. Most intra-ventricular haemorrhages occur in the first 72 hours after birth. They originate in a layer of tissue (Germinal Matrix), under the lining of the ventricles (Ependymal), while it is in the process of manufacturing neurons and glia. This has normally regressed by term but may still be active in premature infants. Pathological investigations have found accumulations of peri-venous plasma and blood suggesting that excessive cerebral venous pressure has disrupted vessels, initiating the intra-ventricular bleeding observed. This has led to unsuccessful searches for evidence of A-V shunts within the developing cerebrum, or loss of auto regulation in arterioles, producing excessive cerebral venous hypertension. An alternative mechanism , reported here, is of venous rather than arterial origin;.. View More»
  DOI: 10.4172/2161-0940.1000202

  Abstract PDF

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