ISSN: 2161-1017
+44 1478 350008
Beizig AM
Tunisia
Research Article
Clinical and Biological Characteristics of Patients Aged 65 and Older with Newly Developed Type 1 Diabetes
Author(s): Ach MT, Njah MK, El Abed YH, Beizig AM, Chadli MC, Ach K
Ach MT, Njah MK, El Abed YH, Beizig AM, Chadli MC, Ach K
Objective: Diabetes of elder subjects is characterized by onset after the age of 65, absence of Ketoacidosis, insulin independence for at least 6 months, and presence of circulating islet-cell antibodies. Its marked heterogeneity in clinical features and immunological markers suggests the existence of multiple mechanisms underlying its pathogenesis.
Methods: This is a retrospective study related to the observation of 5 patients aged over 65 years old, diagnosed with diabetes. All patients have had a dosage of pancreatic antibodies: anti glutamic acid decarboxylase antibodies (GAD antibodies) and tyrosine phosphatase antibodies IA2 (IA2 antibodies), with positivity to at least one of them. Their clinical and biological data, namely clinical aspects, family and personal history, metabolic and biological profile, autoimmune context, and degenerati.. View More»
DOI:
10.4172/2161-1017.1000252