Medical Laboratory Services, Federal Medical Center,
Yenagoa, Bayelsa State
Is Saliva an Alternative Non-Invasive Sample for the Estimation of Protein Profile amongst Diabetics and Gender-based Diagnostics?
Author(s): Agoro E, Ebiere NE, Eseimokumo SA and Odegbemi JOAgoro E, Ebiere NE, Eseimokumo SA and Odegbemi JO
Introduction Protein profile is an important investigation utilized for the diagnosis and management of arrays of diseases such as diabetes mellitus. The measurement of protein profile is basically carried out through invasive sample blood which inflicts pain and is financially cumbersome. The study is aimed at generating an alternative noninvasive sample such as saliva for proteins analysis. Materials and Methods A total of 100 subjects were recruited for the study; 50 subjects diagnosed with type 2 diabetes mellitus and 50 apparently healthy control subjects. Protein profile incudes total protein, albumin, and globulin and albumin/ globulin ratio. Total protein and albumin were estimated using biuret and bromocresol green methods respectively. Globulin and albumin/globulin were estimated mathematically. Result.. Read More»