Journal of Clinical and Cellular Immunology
Open Access

Abstract

Sociodemographic Clinical and Blood Group (ABO/Rh) Profile of Angolan Individuals with HIV

Euclides Nenga Manuel Sacomboio*, Edson Manuel Fragão Agostinho, Adelino Tchilanda Tchivango, Edson Kuatelela Cassinela, Silvana da Rocha Silveira, Mauricio da Costa, Cruz S. Sebastião and Eduardo Ekundi-Valentim

Introduction: Data from UNAIDS in 2021 pointed out that in Angola the number of individuals living with HIV is about 320,000. The system is the most exclusive group polymorphism is associated worldwide and has infected P.falciparum, P.vivax, Candida, H.pylori, HIV, V.B19, and Influenza Virus.

Objective: To evaluate the sociodemographic, clinical, and blood group profile among HIV patients in Luanda, the capital city of Angola.

Methodology: A descriptive, introspective, cross-sectional study with a quantitative approach was carried out with 130 patients from Luanda, in the second half of 2021.

Results: The 130 HIV patients included, the ORh⁺ group (46.9%) was the most predominant, followed by the BRh⁺ groups (25.4%) and ARh⁺ (23.1%). Female gender predominated (59,2%), with a basic level of education (58.5%), single (79.6%), employed (77.7%), living in Luanda Municipality (56.9%). Most patients who became infected having sex without a condom (91.5%), are in stage I of HIV infection (74,6%), and the number of TCD8 cells (20.8%) had an average (between 200 to 1000/mm), 20.8% of them were classified as group I (CD8 TBC greater than 500/mm), most individuals had a high viral load (between 100,000 and 1 million copies). According to the clinical history, the majority lived with the disease from 6 to 10 years (50%), 88.5% were on treatment with a retrovirus, and the majority used a combination of Tenofovir (TDF)+Lamivudine (3TC) or Emtricitabine (FTC)+Efavirenz (EFV) (TDF+3TC+EFV), most of them (54.7%) were undergoing treatment for less than 6 years, however, the statistical analysis showed no relationship between blood groups, and all analyzes (p>0.05).

Conclusion: HIV seems to be common in ORh⁺ individuals and seems to affect mainly women, young people, people with low education, who have a high viral load, infected for less than 6 years, where changes in the blood count occur moderately in individuals of groups O and A and the biochemical changes in individuals A, B and O.

Published Date: 2022-12-19; Received Date: 2022-11-15