The study examined the impact of coping strategies on students’ psychological well-being in a Nigerian university.149 students comprising 81 (54.36%) males and 68 (45.64%) females, ranging from 18 to 33 years, with a meanage of 23.16 years responded to the coping strategies inventory and scales of psychological well-being, via a cross-sectional survey design. The standard multiple regression analysis was adopted to test hypotheses using (SPSS 21version). The results showed significant F (8,140)=7.20, p<0.0005 joint impact of coping strategies on psychologicalwell-being, and accounted for approximately 29.2% of the variability. Independently, there were significantindependent positive and negative impacts of coping strategies dimensions on psychological well-being. Based onthe findings, the researcher concluded that coping strategies may enhance and/or exacerbate psychological well-being. Students are advised among others to embrace appropriate strategies to avoid negative consequences.