Journal of Clinical & Experimental Dermatology Research
Open Access

Abstract

Surgical Site Infection Rate of PDS-II and Dermabond Versus Vicryl and Silk in Major Abdominal Surgery Using the Pig Liver Resection Model

Mitsugi Shimoda

Aim: PDS-II for peritoneal and subcuticular sutures, followed by Dermabond for skin dressing was commonly used in minimal surgical field, it is still unclear whether subcuticular closure and skin dressing are effective for the major abdominal surgical incision. The purpose was to investigate SSI of PDS-II and Dermabond versus Vicryl and silk in major abdominal surgery using the pig liver resection mode.
Methods: A chevron incision was performed, followed by the left hemi-hepatectomy using pig liver. In group A, the closing of the peritoneum and subcuticular tissue were done using 1 and 3-0 PDS-II. Dermabond was used for skin dressing. In group B, closing materials were using 1-0 viclyl at peritoneal and 2-0 silk at submucosa and skin. We evaluated SSI of the skin incision in both groups.
Results: We evaluated 7 pigs in each groups. In group A, only one of the seven pigs (14.3%) had superficial incisional SSI. In group B, Five out of seven pigs (71.4%) had deep incisional SSI and ventral hernia, and they were died within 10-14 days after surgery. Group A was significantly lower incidence of SSI than group B (P=0.03).
Conclusion: PDS-II and Dermabond were effective for abdomal closing.