Introduction: There is evidence that schoolbags may be a contributing factor for musculoskeletal complaints in schoolchildren. Several studies have reported an association between carrying heavily loaded schoolbags and pain or discomfort. Methods: 105 collegiate students were conveniently recruited in this study; heart rate (HR) and perceived exertion were measured immediately after the treadmill walking with the back pack, right side pack and left side pack. Subject has to walk for 20 min after that the HR was measured using pulse oximeter and perceived exertion was measured using Borg’s RPE scale. Results: It showed there is a significant increase in RPE with right side pack, with left side pack and with back pack after treadmill walking. Conclusion: Ratings of Perceived Exertion (RPE) increased after treadmill walking with carrying load in right side pack, left side pack and back pack.