Armel Poda* , ArsÃÂ¨ne HÃÂ©ma, Adrien Sawadogo, Ibrahim Sawadogo, Issouf YamÃÂ©ogo, Jacques Zoungrana, ZiemlÃÂ© ClÃÂ©ment MÃÂ©da, Firmin KaborÃÂ©, Boly Rainataou, InÃÂ¨s Da, ChÃÂ©rileila Thiombiano, HervÃÂ© Kpoda, Abdoul Salam OuÃÂ©draogo, Guillaume Bado, Ismael Diallo, DiendÃÂ©rÃÂ©Eric, Apoline Sondo, Mamoudou Savadogo, TÃÂ©nÃÂ© Marceline YamÃÂ©ogo
Background: in sub-Saharan Africa, the co-morbidity of diabetes mellitus and HIV is still poorly assessed. This study
aimed to determine the incidence and risk factors of diabetes mellitus among PHAs with HIV followed on an
outpatient basis at the adult day hospital (HDJ) in Bobo-Dioulasso, Burkina Faso.
Methods: A retrospective cohort study was conducted and concerning period from January 2008 to December 2015
at the adult HDJ. The diagnosis of diabetes mellitus was based on the basis of 2 blood glucose levels >7 mmol/l or
patient having a status of diabetes mellitus confirmed. The Cox proportional risk method was used to identify risk
factors for the development of diabetes mellitus. The significance level was set at p value < 5% for all statistical tests.
Data were analyzed by STATA13 software.
Results: we included 4,500 patients. The incidence of diabetes mellitus was 4.7 per 1000 person-years. Diabetic
subjects were predominantly infected with HIV1 (89.4%); the age group 36-45 years was the most represented
(34.6%). We observed a predominance of females (61.5%) and an abnormal body mass index (BMI) for 42.9% of
The majority of diabetics were detected at WHO stage 3 (42.5%), had arterial hypertension (38.0%), had abnormal
glomerular filtration rate (30.0%) and had CD4 counts of less than 350 cells/μl for 70.0% of the cases. among them
38% had hypertension; 30% had abnormal glomerular filtration rate and 70% had a low CD4 count of less than 350
cells/μl. In multivariate analysis only age >55 years was identified as an independent risk factor for the occurrence of
diabetes mellitus during follow-up.
Conclusion: Diabetes mellitus was found among PLWHIV from the day hospital cohort in Bobo Dioulasso. Age was
the risk factor found for the onset of diabetes. Integrated approach for patient’s management in different units in
sub-Saharan Africa is suitable facing double epidemiological burden.
Published Date: 2020-01-30; Received Date: 2020-01-09