Journal of Clinical Microbiology and Antimicrobials
Open Access

Abstract

In Vivo Antibacterial Effectiveness of the Otological Solution Based on Spondias Mombin L. in the Treatment of External Otitis in Dogs

Jonas Santos Silva, Francisco Marlon Carneiro Feijo*, Nilza Dutra Alves, Gardenia Silvana Oliveira Rodrigues, Caio Sergio Santos, Alexsandra Fernandes Pereira, Eninara Vanesca da Silva Moreira, Leticia Caetano Siqueira, Leon Denner Moreira Benicio, Ribeiro, Yara Stephanne Ramos Ribeiro and Matheus Barbosa Nascimento

Aim: This research evaluated the effectiveness of the otological solution based on cajá leaves (Spondias mombin L. -SM) as a therapeutic alternative in the treatment of bacterial external otitis in dogs.

Methodology and results: For that, 20 dogs, without sex, breed and defined ages were divided into four groups, the first group used 2% SM diluted in glycerin and applied 24/24 h, the second group used 2% SM diluted in glycerin and applied 12/12 h, the third group as a positive control ciprofloxacin at 3.5% and the fourth group with SM at 20% applied 12/12 h. After 21 days of treatment, the alternative antimicrobial SM at 2% diluted in glycerin and applied for 12/12 h showed a reduction in the Colony Forming Unit (CFU) with no statistical difference from ciproflaxacin, no toxicological changes on the parameters of morphology, viability and epithelial cell activity.

Conclusion: The use of Spondia mombin reduced the number of bacterials and the clinical signs evaluated, proving its effectiveness as a treatment for otitis in dogs.

Published Date: 2022-11-14; Received Date: 2022-10-11