A cross sectional, descriptive interventional study directed by four research questions and three hypotheses was used to determine the impact of health education on knowledge, attitude and practice of cervical cancer screening among secondary school teachers. Population was secondary school teachers in Enugu State. Sample size of 380 teachers in 14 schools in Enugu North Local Government Area was drawn as sample using multi-stage sampling technique. Instrument used was questionnaire. Data were presented in tables and analyzed using measures of central tendencies and percentages. Hypotheses were tested using chi-square. Findings revealed relative good knowledge, positive attitudes, poor practice and significant impact of health education on their knowledge, attitude and practice. Recommendations were made as well as suggestions for further studies.