Journal of Alcoholism & Drug Dependence
Open Access
ISSN: 2329-6488
ISSN: 2329-6488
Lina Schneider*
The intricate relationship between Early-Life Trauma (ELT) and the development of Alcohol Use Disorder (AUD) in adulthood has become a subject of increasing interest within neuroscience and addiction medicine. Early exposure to traumatic experiences such as emotional neglect, physical abuse, or loss of a caregiver not only disrupts normal psychological development but also induces long-lasting alterations in brain circuitry that predispose individuals to substance use as a maladaptive coping strategy. In recent years, neuroimaging and biomolecular studies have provided compelling evidence that trauma during formative years can permanently shape neural pathways involved in stress regulation, emotional processing, and reward sensitivity three systems closely linked to the pathophysiology of AUD.
Published Date: 2025-03-04; Received Date: 2025-02-03