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Objective: To review the literature on Obstructive Sleep Apnea (OSA) and Health Related Quality of Life (HRQoL).
Method: We conducted systematic review of the literature on HRQoL and OSA.
Summary: Our review of published literature on quality of life in adult OSA suggest that there is significant impairment of HRQoL in obstructive sleep apnea but the magnitude of QoL impairment is not proportional to the severity of OSA as determined by AHI. There is paucity of data over effect of treatment on quality of life but the available data suggest that there is improvement in QoL with CPAP treatment at least in moderate and severe OSA patients. Effect of other treatment modalities is unclear yet.