Journal of Clinical and Cellular Immunology
Open Access

Abstract

Gluten, Transglutaminase, Celiac Disease and IgA Nephropathy

Aaron Lerner, Laureline Berthelot, Patricia Jeremias, Torsten Matthias, Lilia Abbad and Renato C Monteiro

Both, celiac disease and IgA nephropathy are autoimmune diseases that are IgA mediated and share multiple clinical, pathophysiological, genetic, nutritional and immunological aspects. In view of recent observations and wider understanding of the central role played by the intestinal ecosystem in celiac disease and IgA nephropathy development, the present review highlights those shared aspects, concentrating on potential nutritional therapeutic strategies in IgA nephropathy.