The present study aimed to evaluate the aqueous extracts from the leaves of Catharanthus roseus L. and Lantana camara L. against filarial vector mosquito Culex quinquefasciatus Say and dengue vector Aedes aegypti L. The plant material was macerated and extracted with distilled water. The aqueous extract was tested at different concentrations of 1000, 500, 250, 125 and 62.5 ppm concentrations against I, II, III and IV instar larvae of C. quinquefasciatus and A. aegypti. The LC50 values of C. roseus against I, II, III and IV instar larvae of C. quinquefasciatus were 30.28, 38.01, 59.12 and 71.81 and against A. aegypti 26.64, 34.64, 53.10 and 72.89 ppm. The LC50 values of L. camara against I, II, III and IV instar larvae of C. quinquefasciatus were 35.48, 46.74, 67.64 and 95.51 and against A. aegypti 35.19, 38.26, 65.98 and 91.90 ppm. No mortality of was observed in control. Our results suggest that the aqueous extract of C. roseus have the potential to be used as an ecofriendly approach for the control larvae of vector mosquito C. quinquefasciatus and A. aegypti.