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Ryma Kebbab-Massime, Brahim Labed and Rabia Boutamine-Sahki
The objective of this study is to evaluate the antioxidant activity and antibacterial activity of the methanolic extracts obtained by using organic solvents with increasing polarity of leaves of Solenostemma argel, a medicinal plant of the traditional pharmacopeia of Tamanghasset (great Sahara) of Algeria. Initially, after extraction obtained by maceration of S. argel, the amount of total flavonoids isolated in the four extracts (ether, ethyl acetate, butanolic and aqueous extracts) was given, and by thin layer chromatography, profiles of each extract is obtained. The proportion of the flavonoids of these same extracts showed the wealth of this plant on total flavonoids. The antioxidant activity was evaluated by using 2, 2-Diphenyl-1-picrylhydrazyl (DPPHï) radical scavenging assay and the antibacterial effect of these extracts was evaluated by using the agar diffusion method on three bacterial strains. The results reveal that, only the ether extract of the plant collected in the area of Adrian (AD) exerted a considerable antibacterial effect only against Pseudomonas aeruginosa with zones of inhibition (09 mm and 08 mm). With final, the extracts of S. argel have an excellent antioxidant activity and a weak antibacterial effect.