Journal of Drug Metabolism & Toxicology
Open Access

Abstract

Drug Transporters: Gatekeepers of Drug Disposition and Therapeutic Response

Kovur Zahra*

Drug transporters are membrane-bound proteins that control the movement of drugs and other xenobiotics across cellular membranes. These transporters play a critical role in the Absorption, Distribution, Metabolism and Excretion (ADME) of drugs. By mediating drug entry into and out of cells, they influence drug bioavailability, efficacy, toxicity, and the development of drug resistance. Understanding drug transporters is vital in pharmacology, drug development, and personalized medicine.

Published Date: 2025-03-04; Received Date: 2025-02-03