Journal of Applied Pharmacy
Open Access

Abstract

Development and Clinical Evaluation of Mucoadhesive Buccal Films for Rapid Pain Relief

Camila Rodríguez Torres*

The increasing demand for patient-friendly drug delivery systems has catalyzed the development of novel pharmaceutical formulations that ensure both therapeutic efficiency and enhanced patient compliance. Among these innovations, mucoadhesive buccal films have garnered significant attention for their ability to provide rapid and localized pain relief. These thin, flexible films are designed to adhere to the buccal mucosa, facilitating the direct absorption of drugs into the systemic circulation while bypassing first-pass hepatic metabolism. This delivery route not only accelerates onset of action but also reduces dosing frequency and gastrointestinal side effects, making it particularly suitable for acute pain management. In Mexico, where pain management remains a clinical priority in both outpatient and emergency care, the implementation of mucoadhesive buccal films offers a promising alternative to conventional oral and parenteral routes.

Published Date: 2025-03-04; Received Date: 2025-02-03