Journal of Applied Pharmacy
Open Access

Abstract

DEGRADATION AND INACTIVATION OF CIPROFLOXACIN BY PHOTOCATALYSIS USING TIO2NANOPARTICLES

Imran Hayder, Ishtiaq A.Qazi,M.Ali Awan, Muhammad Arshad Khan,Aftab Turabi

To compare Ciprofloxacin attenuation efficiency, Ciprofloxacin solutions mixed with TiO2nanoparticles were irradiated with two different light sources: a UV lamp and ordinary electric bulb. Insignificant degradation was witnessed when irradiations were made in absence of TiO2. In contrast, prominent Ciprofloxacin degradation was detected in the presence of 0.01 mg/ml of TiO2. Close to 90 % and 70 % of its original concentration was eradicated in 120 minutes when the irradiation basis used was a UV lamp and Ordinary electric bulb respectively. Without the use of TiO2 nanoparticles, irradiation by UV lamp sources was also significant. The antibactacterial activity of chosen microorganisms was radically inhibited when exposed to Ciprofloxacin solution treated with photocatalyst for the short periods of irradiation.