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Combined Evidence from Individual Cases over Half a Hundred Years Collected Globally | Abstract
Journal of Pharmacological Reports

Journal of Pharmacological Reports
Open Access

Abstract

Combined Evidence from Individual Cases over Half a Hundred Years Collected Globally

Sarah Watson*

Adverse drug reactions (ADRs) are a crucial explanation for morbidity and mortality. Reports on differences in reporting patterns between women and men exist nationally. The goal of this study was to assess the worldwide evidence on spontaneous post-marketing ADR reporting differences be- tween reports for ladies and men. Methods: We analysed data collected within VigiBase, the WHO global database of individual case safety reports, between 1967-2 January 2018. VigiBase contains quite 18 million reports from the 131 mem- ber countries of the WHO Programme for International Drug Monitoring. Findings: Of the reports with information on sex, 9,056,566 (60.1%) concerned female and 6,012,804 (39.9%) male children and adults. More female ADR reports were submitted altogether regions of the planet and by all kinds of reporters. A higher proportion of female reports was seen altogether age bracket s from the age group 12-17 years and older. The largest difference was observed within the age group of 18–44 years and can not be explained by hormonal contraceptive use. The proportion of great and fatal reports was higher for male reports.

Published Date: 2021-07-26; Received Date: 2021-07-12

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