Mohammad Abid Keen, Swati Watwani
Cyclic premenstrual physiological changes in healthy skin and various dermatoses represent common ailments reflecting the direct or indirect response of skin to fluctuations in circulating sex steroid hormones. A subset of chronic dermatoses are not specifically induced but are merely exacerbated at the end of the ovarian cycle, while as catamenial eruptions are specifically restricted to only the menstruation periods. Thus, catamenial dermatoses may be defined as cyclical skin reactions to hormones produced during the menstrual cycle.(1,2) The most common of these reactions is autoimmune progesterone dermatitis (APD), caused by an autoimmune response to endogenous progesterone in women of reproductive age.(3) It has an onset anytime between menarche and menopause and is clinically characterized by a myriad of presentations including urticaria, eczema, papulovesicles, angioedema, anaphylaxis, pruritus and erythema multiforme.
Published Date: 2021-09-10;