Orthopedic & Muscular System: Current Research
Open Access

Abstract

Atypical Bilateral Femur Fractures in a Long-Term Bisphosphonate Therapy: A Case Report

Roberto Valentini, Alessandro Moghnie, Veronica Scamacca, Marcellino Martino, Silvia Perin and Luigi Murena

Atypical Femur Fractures (AFF) are associated with Bisphosphonate Osteoporosis Therapy. Bisphosphonate therapy is widely used as the Gold-Standard Therapy for Osteoporosis: it increases bone density and reduce the risk of vertebral, non-vertebral and hip fractures. However, long-term alendronic acid administration can causes severely suppressed bone turnover and finally non-traumatic stress fractures. Here we present a case of Non-Traumatic stress fractures of bilateral femoral shafts in a Long-Term Alendronic Acid Therapy.