Background: To assess the properties of regular yoga training on oxidative stress and antioxidant components, including total glutathione (GSH) and its redox systems (GSH-peroxidase and reductase), total antioxidant capacity (TAC), and activities of superoxide dismutase (SOD) and catalase in healthy university students. Study design and methods: Current study involved total 25 of healthy participants who were divided into two groups as control and regularly yoga group. All subjects undertook the regularly control or yoga program for 90 minutes, once every week, for 12 weeks under the care of yoga and health professional instructor. Before the start and end of each program, the serum level of oxidative stress and antioxidant components were estimated. Results: The serum MDA level considerably decreased in yoga training group and significantly increased TAC levels, total GSH contents and SOD activities the serum level (P < 0.05 or P < 0.01) as compared with the changes value of control care program. Conclusions: From the results, present study supports the utility of yogic exercises as a remedy to control or check oxidative stress in the healthy volunteers.