Both yoga and exercise have been suggested as an effective method of alleviating depressive disorders, along with being shown to uplift mood and increase positivity, even when not clinically depressed. Objectives: The aim of this trial was to examine the efficaciousness of yoga and exercise in acutely improving mood in non-depressed participants. Methods: This study involved female participants of a yoga group (n=8) and an exercise group (n=7). Participants completed a Profile of Mood States (POMS) questionnaire before undertaking a sixty minute class. An identical POMS questionnaire was then completed immediately after the class had ended. Results: There was a main effect of trial (p=0.049) on anger; participants of the exercise class displayed higher levels of anger than participants of yoga. There was no main effect on fatigue for trial or time (p=0.244 and p=0.270 respectively). There was a main effect of time on tension/anxiety (p<0.001), depression/dejection (p=0.009), anger/hostility (p=0.011), vigour/activity (p<0.001) and confusion/bewilderment (p=0.001). Both yoga and exercise improved these mood states. Conclusion: Exercise and yoga significantly increase vigour, and reduce depression, tension, confusion, anxiety and anger. Both are invigorating to participants and provide an uplifting effect and increase in feelings of positivity; they would be a viable method of self-treatment for people experiencing low mood. With further research, exercise and yoga would be a viable option of an alternative or adjunct to medication.