Foundational lupus erythematosus (SLE) is an immune system sickness. In this ailment, the resistant arrangement of the body erroneously assaults sound tissue. It can influence the skin, joints, kidneys, cerebrum, and different organs. Lupus (SLE) can affect the joints, skin, kidneys, blood cells, brain, heart and lungs. Symptoms vary but can include fatigue, joint pain, rash and fever. These can periodically get worse (flare up) and then improve.While there's no cure for lupus, current treatments focus on improving quality of life through controlling symptoms and minimising flare-ups.