Journal of Cell Science & Therapy
Open Access

Research Articles In Histopathology

Histopathology is the study of changes in any tissue, animal or plant, associated with a disease or disorder . In the medical context, the examination starts with sampling, either during a surgical procedure or autopsy, after which the tissue is processed for viewing under a microscope. Forensic histopathology deals with the assessment of histological findings in any forensically relevant context and their significance as forensic evidence, with the ultimate goal to serve proper administration of justice. An autopsy is not complete and reviewable without histology. Clinical/surgical histopathology is beyond the scope of this article. Histologically, deep palmoplantar warts are characterized by endophytic growth of epidermis with hyperkeratosis, hypergranulosis, papillomatosis, and elongated and inward bending of the peripheral rete ridges . There are numerous homogeneous eosinophilic bodies within the cytoplasm of keratinocytes in the upper malpighian layer. In addition to these bodies, some of the cells in the upper malpighian layer with vacuolar nuclei show a small intranuclear eosinophilic inclusion body. The keratinocytes in the granular layer show coarse keratohyalin granules and perinuclear vacuolization.