Journal of Cancer Science and Research
Open Access

Cancer Biology Online Journals

Cancer describes an enormous spectrum of diseases that all originate from uncontrolled cellular growth. Broadly divided into benign tumors (unable to metastasize) or malignant tumors (able to invade normal tissues), cancers are further defined and classified by their cell type, tissue, or organ of origin. Opportunities in Cancer Biology Research New genetic technologies developed over the past decade have helped researchers examine the functional effects of genetic alterations that underlie the development of cancer. These tools have also been used to study epigenetic changes associated with cancer, mechanisms of DNA damage and repair, and gene regulation in cancer cells. The introduction of increasingly powerful structural biology approaches has allowed researchers to characterize the structures of mutant proteins involved in cancer, such as RAS, and other molecules in greater detail than had been possible previously. And through approaches that allow the characterization of the entire proteome, researchers are integrating genomic analysis with the analysis of the proteins in tumor cells to learn, in detail, how cancer-associated mutant proteins affect other proteins.