Transfection of Endothelial Nitric Oxide Synthase Gene Improves Angiogenic Efficacy of Endothelial Progenitor Cells in Rabbits with Hindlimb Ischemia

Savneet Kaur¹, VS Harikrishnan², Sachin J Shenoy², NS Radhakrishnan³, Akira Uruno⁴, Akira Sugawara⁴ and Chandrasekharan C Kartha^5*

¹Division of Cellular and Molecular Cardiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram 695011, India

²Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram 695014, India

³Division of Pathology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram 695011, India

⁴Department of Medicine, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan

⁵Disease Biology and Molecular Medicine, Rajiv Gandhi Center for Biotechnology, Thiruvananthapuram 695014, India

⁶School of Biotechnology, Gautam Buddha University, Greater Noida, UP- 201308, India

^*Corresponding Author: Chandrasekharan C Kartha, Department of Disease Biology & Molecular Medicine, Rajiv Gandhi Center for Biotechnology, Thiruvananthapuram 695014, India, Tel: 91-471-2529448, Fax: 91-471-2348096 Email: