Journal of Nanomedicine & Biotherapeutic Discovery
Open Access

Abstract

Conventional cancer treatments face limitations, driving the exploration of combination therapy for enhanced effectiveness. This study introduces a innovative approach by utilizing Diatom-Derived Mesoporous Silica Nanoparticles (dMSN) enriched with lanthanide metal ions, enabling dual-action therapy. These nanoparticles not only exhibit photodynamic therapy capabilities but also offer MRI and fluorescence imaging functions. Incorporating fucoidan, a potent natural anticancer agent from brown algae, the study achieves remarkable efficacy against drug-resistant cancer cells. The combination of dMSN-EuGd@Fucoidan outperforms standalone photodynamic therapy or chemotherapy, presenting a robust solution for cancer treatment. Leveraging the unique properties of diatoms, the most prevalent group in the ocean, aligns with sustainable healthcare principles. In summary, this research pioneers a combined chemo-photodynamic therapy system, harnessing the advantages of fucoidan and innovative diatom-derived nanoparticles. It addresses drug resistance and suboptimal drug delivery, moving us closer to more effective and targeted cancer treatment

Author Info

Citation: Lin HM (2023) Diatom-derived Mesoporous Silica Nanoparticles Loaded with Fucoidan for Enhanced Chemo-Photodynamic Therapy. J Nanomedicine Biotherapeutic Discov. 13:221.

Received: 25-Oct-2023, Manuscript No. JNBD-23-27787; Editor assigned: 27-Oct-2023, Pre QC No. JNBD-23-27787 (PQ); Reviewed: 10-Nov-2023, QC No. JNBD-23-27787; Revised: 20-Nov-2023, Manuscript No. JNBD-23-27787 (R); Published: 27-Nov-2023

Copyright: © 2023 Lin HM. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.