Journal of Developing Drugs

Journal of Developing Drugs
Open Access

ISSN: 2329-6631

Research Article - (2017) Volume 6, Issue 3

The Relationship of Polymorphism of RFC-I Gene on Methotrexate Serum Level and Related Toxicity in Pediatric Acute Lymphoblastic Leukemia

Zaker F1,2*, Ansari S3, Toosi B2, Sayadi M4 and Sharafi H2
1Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran
2Departement of Hematology, School of Allied Medical Sciences, Iran University of Medical Sciences, Tehran, Iran
3Departement of Pediatric Hematology and Oncology, Aliasghar Hospital, Iran University of Medical Sciences, Tehran, Iran
4Departement of Hematology, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran
*Corresponding Author: Zaker F, School of Allied Medical Sciences and Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran, Tel: +982186701021 Email:

Abstract