Targeting of Interleukin-6 for the Treatment of Rheumatoid Arthritis: A Review and Update

Toshio Tanaka^1,2*, Atsushi Ogata^2,3 and Tadamitsu Kishimoto⁴

¹Department of Clinical Application of Biologics, Osaka University Graduate School of Medicine, Osaka University, Osaka, Japan

²Department of Immunopathology, WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan

³Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine, Osaka University, Osaka, Japan

⁴Laboratory of Immunoregulation, WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan

^*Corresponding Author: Toshio Tanaka, Department of Clinical Application of Biologics, Osaka University Graduate School of Medicine, 2-2 Yamada-oka, Suita City, Osaka 565-0871, Japan, Tel: +81-6-6879-3838, Fax: +81-6-6879-3839 Email: