Supramolecular Targeting of B16F10 Melanoma Cells With Nanoparticles Consisting of a DEAE-Dextran-MMA Copolymer-Paclitaxel Complex In vivo and In vitro

Yuki Eshita^1*, Rui-Cheng Ji², Masayasu Onishi³, Lucky Ronald Runtuwene¹, Kaori Noguchi¹, Takashi Kobayashi¹, Masaaki Mizuno⁴, Jun Yoshida⁵, Naoji Kubota⁶ and Yasuhiko Onishi¹

¹Department of Infectious Disease Control, Oita University, 1-1 Idaigaoka, Hasama-machi, Yufu, Oita 879-5593, Japan

²Department of Human Anatomy, Oita University, 1-1 Idaigaoka, Hasama-machi, Yufu, Oita 879-5593, Japan

³Ryujyu Science Corporation, 39-4 Kosora-cho, Seto, Aichi 489-0842, Japan

⁴The Center for Advanced Medicine and Clinical Research, Nagoya University Hospital, 65 Tsurumai-cho, Showaku, Nagoya, Aichi 466-8560, Japan

⁵Chubu Rosai Hospital, Japan Labor Health and Welfare Organization, 1-10-6 Komei, Minato-ku, Nagoya, Aichi 455-8530, Japan

⁶Department of Chemistry, Oita University, 1-1 Idaigaoka, Hasama-machi, Yufu, Oita 879-5593, Japan

^*Corresponding Author: Yuki Eshita, Department of Infectious Disease Control, Oita University, 1-1 Idaigaoka, Hasama-machi, Yufu Oita 879-5593, Japan Email: