Structure based Functional Distinction between Cln1 and Cln2 Depends on the Ubiquitin-Proteasome Pathway

Akiko Suganami^1*, Norio Takase¹, Hajime Sugiyama², Eric V Virtudazo³, Susumu Kawamoto³ and Yutaka Tamura¹

¹Department of Bioinformatics, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan

²Bio IT Development, Fujitsu Limited, Chiba 261-8588, Japan

³Division of Molecular Biology, Medical Mycology Research Center, Chiba University, Chiba 260-8673, Japan

^*Corresponding Author: Akiko Suganami, Department of Bioinformatics, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan, Tel: +81-43-226-2813