Gynecology & Obstetrics
Open Access

Abstract

Introduction: Pregnant women with sickle cell disease have a high risk of morbidity and mortality. Objective : This study sought to investigate the maternal and neonatal prognosis of sickle cell disease from 2017 to 2021 at the Departmental University teaching Hospital of Borgou (CHUD/B). Method: This was a retrospective cross-sectional study with descriptive and analytical purposes, carried out in the mother-child department and intensive care unit of the Departmental University teaching Hospital of Borgou (CHUD/B). Data collection was carried out from February 5, 2022 to June 5, 2022. A non-probability sampling technique with exhaustive recruitment of participants meeting the inclusion criteria was used. Pearson's Khi2 or Fisher's exact tests were used accordingly. Result: A total of 128 medical records of sickle cell pregnant women were reviewed with 97 (75.8%) SC type and 31 (24.2%) SS type. The hospital frequency of sickle cell disease was 0.99%. The most frequent childbirth route in these women was caesarean section (90.6%) of which 72.16% was prophylactic with the sole indication of sickle cell disease. The main complications found following childbirth were severe anemia (66.7%), vaso-occlusive crisis (29.6%), and puerperal infection (25.8%). Maternal mortality related to sickle cell disease was 11.72% while neonatal mortality was 8.1%. In addition, SS sickle cell patients were more likely to be anemic (p=0.0320), to be transfused (p=0.0086) and to give birth to a baby deceased in utero (p=0.016) than SC sickle cell patients. The fetal prognosis is twice as bad in SS sickle cell women than in SC women (p=0.049). Conclusion: Pregnancy on sickle cell disease is associated with multiple prenatal and postnatal complications at the CHUD-B. SS women are more likely to have more complications than SC women.

Author Info

Received: 29-Aug-2023, Manuscript No. gocr-23-26363; Editor assigned: 01-Sep-2023, Pre QC No. gocr-23-26363(PQ); Reviewed: 15-Sep-2023, QC No. gocr-23-26363(Q); Revised: 25-Sep-2023, Manuscript No. gocr-23-26363(R); Accepted: 02-Oct-2023 Published: 15-Oct-2023

Copyright: This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.