Proteomic Profiling of Ewing Sarcoma Reveals a Role for TRAF6 in Proliferation and Ribonucleoproteins/RNA Processing

Juan Madoz-Gurpide^1*, David Herrero-Martin², Gonzalo Gomez-Lopez³, Lourdes Hontecillas-Prieto⁴, Michele Biscuola⁴, Cristina Chamizo¹, Daniel Garcia-Dominguez⁴, David Marcilla⁴, Ana Teresa Amaral⁴, Jose Luis Ordonez⁵ and Enrique De Alava^4*

¹Cancer Biomarkers Research Group, Health Research Institute Fundación Jiménez Díaz (IIS-FJD), UAM, Madrid, Spain

²Sarcoma Research Group, Bellvitge Biomedical Research Institute, Barcelona, Spain

³Bioinformatics Unit, Spanish National Cancer Research Centre (CNIO), Madrid, Spain

⁴Pathology Unit, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain

⁵Molecular Cytogenetics, Centro de Investigación del Cáncer-IBMCC, Universidad de Salamanca-CSIC, Salamanca, Spain

^*Corresponding Author(s): Juan Madoz-Gurpide, Cancer Biomarkers Research Group, IIS-Fundación Jimenez Diaz, UAM, Avda. Reyes Católicos 2, E-28040, Madrid, Spain, Tel: +34-915504804 Enrique De Alava, Pathology Unit, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocio/CSIC/Universidad de Sevilla, Avda. Manuel Siurot S/n, E-41013, Seville, Spain, Tel: +34- 955923089