Potential New Markers of Inflammation-Induced Renal Injury Subside when Endotoxin Tolerance Develops in Humans

Rosalinde Masereeuw^2*, Annelies Draisma¹, Suzanne Heemskerk², Martijn PWJM Bouw¹, Coby Laarakkers³, Johannes G Van Der Hoeven¹ and Peter Pickkers¹

¹Department of Intensive Care Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

²Department of Pharmacology and Toxicology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

³Department of Laboratory Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

^*Corresponding Author: Rosalinde Masereeuw, Department of Pharmacology and Toxicology (149), Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB, Nijmegen, The Netherlands, Tel: +31-24-3613730, Fax: +31-24- 3614214