Organophosphate Detection in a Homicide Victim Burned After Death
Journal of Clinical Toxicology

Journal of Clinical Toxicology
Open Access

ISSN: 2161-0495

+44 1478 350008

Editorial - (2013) Volume 3, Issue 3

Organophosphate Detection in a Homicide Victim Burned After Death: Deciding the Cause of Death

Akhgari Maryam1* and Etemadi-Aleagha Afshar2
1Legal Medicine Research Center, Legal Medicine Organization, Tehran, Iran
2Tehran University of Medical Sciences, Faculty of Medicine, Amir, Alam Hospital, Tehran, Iran
*Corresponding Author: Akhgari Maryam, Legal Medicine Research Center, Legal Medicine Organization, Tehran, Iran Email:


Poisonings, whether intentional or unintentional, induced by others or self-induced, always have medicolegal implications. Several difficulties come with the detection of homicidal deaths. Presenting signs and symptoms are often misdiagnosed as natural death or suicide, especially if the crime is committed in a friendly environment [1,2]. Thus, an unknown number of homicides go undetected. In this paper, we report our experience with one case in which there was a homicide committed in association with use of large amounts of organophosphates.

Materials and Methods

The body of a 34-year-old woman was brought for post-mortem examination to Legal Medicine Organization of Iran, Tehran to clarify the cause of death. Forensic examinations were performed under the supervision of forensic medicine specialists. The body was burnt totally and no evidence of violence could be detected. For qualitative analysis, Thin-Layer Chromatography (TLC), High-Performance Liquid Chromatography (HPLC) and Gas Chromatography/Mass Spectrometry (GC/MS) techniques were used to screen and confirm the presence of drugs, poisons and opioid alkaloids in biological samples. Forensic toxicology examinations were done on blood, liver, stomach content and bile by GC/MS, HPLC, spectrophotometry.


Carboxy hemoglobin was not found in victim’s blood and burns injuries were postmortem in nature. No coal pigment was observed in the mucosa of the upper airways at autopsy. Sulfotep, ethion and diazinon organophosphates were detected in stomach content not in liver sample by GC/MS instrumentation. Bile sample was positive for trimipramine and phenobarbital. Postmortem burn and absence of carboxy hemoglobin from victim’s blood and unusual evidences in crime scene investigation were favored to put this case in homicidal category. These findings reflect that the victim was already dead at the time of fire. Her husband made a confession to the police soon after her death. He said that during a quarrel with her wife he pressed over her neck and after her death, he poured a gallon of organophosphate pesticide in victim’s mouth and had burnt her body.


Homicidal poisoning involving pesticides has always been rare owing to their disagreeable odor and taste. One of the most difficult tasks in forensic medicine is deciding the cause of death in an unclear or debatable case. Most decision-making difficulties arise when there is a definite or potential causal interaction between evidences in crime scene investigation and circumstantial events. Thus, care should be taken when interpreting positive analytical toxicology results.


  1. Finnberg A, Junuzovic M, Dragovic L, Ortiz-Reyes R, Hamel M, et al. (2013) Homicide by poisoning. Am J Forensic Med Pathol 34: 38-42.
  2. Roth R (2009) Distinguishing Homicides from Natural Deaths, Accidental Deaths, Suicides, and Feigned Deaths (DH). A supplement to Randolph Roth, American Homicide. The Belknap Press of Harvard University Press.
Citation: Akhgari M, Etemadi-Aleagha A (2013) Organophosphate Detection in a Homicide Victim Burned After Death: Deciding the Cause of Death. J Clin Toxicol 3:e116.

Copyright: © 2013 Maryam A. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.