Novel Isozyme-Specific Quantitation Method for Alpha-Amylases in Human Plasma Revealed Possible AMY2B Induction by Alpha-Amylase Inhibitor, CS-1036

Mayumi Hayashi¹, Toshiyuki Kosaka², Mitsunori Kato¹, Tomohiro Honda³, Takuo Washio⁴, Atsushi Yamasaki⁵, Kazuishi Kubota^1* and Akira Shinagawa¹

¹Discovery Science and Technology Department, Daiichi Sankyo RD Novare Co., Ltd, Japan

²Translational Medicine and Clinical Pharmacology Department, Daiichi Sankyo Co., Ltd, Japan

³Drug Discovery Technology Function, Asubio Pharma Co., Ltd, Japan

⁴Asia Development Department, Daiichi Sankyo Co., Ltd, Japan

⁵Daiichi Sankyo Pharma Development, Daiichi Sankyo, Inc, Japan

^*Corresponding Author: Kazuishi Kubota, Discovery Science and Technology Department, Daiichi Sankyo RD Novare Co., Ltd, Japan, Tel: +81-80-4468-2489