Murine Model of Neuroschistosomiasis Mansoni: Clinical, Histological and Magnetic Resonance Imaging Studies

Thiago Andre Alves Fidelis^1,2*, Patricia Parreiras², Fernanda Tovar-Moll³, Fernanda Meireles³, Geraldo Brasileiro Filho⁴, Paulo Marcos Zech Coelho² and Jose Roberto Lambertucci¹

¹Division of Infectology and Tropical Medicine, Department of Internal Medicine, School of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil, E-mail: profeta@cpqrr.fiocruz.br

²Schistosomiasis Laboratory, Rene Rachou Research Center, Oswaldo Cruz Foundation (Fiocruz), Belo Horizonte, Minas Gerais, Brazil, E-mail: profeta@cpqrr.fiocruz.br

³CENABIO/Universidade Federal do Rio de Janeiro, Brazil, E-mail: profeta@cpqrr.fiocruz.br

⁴Department of Pathology, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil, E-mail: profeta@cpqrr.fiocruz.br

^*Corresponding Author: Thiago Andre Alves Fidelis, Physical Therapist, Universidade Federal de Minas Gerais, Infectious Diseases, Alfredo Balena Avenue 190, Belo Horizonte Minas Gerais 30130-100, Brazil, Tel: +55 31 994208520, Fax: +55 31 994208520 Email:

Keywords: Schistosomiasis; Schistosomiasis mansoni ; Neuroschistosomiasis murine model; Encephalitis; Neuroinfection

Introduction