Metformin Reduces Left Ventricular Eccentric Re-modeling In Experimental volume Overload in the Rat

Wahiba Dhahri¹, Élise Roussel¹, Marie-Claude Drolet¹, Suzanne Gascon², Otman Sarrhini², Jacques A. Rousseau², Roger Lecomte², Jacques Couet^2* and Marie Arsenault^1*

¹Group valvulopathies Research, Research Center, Institute of Cardiology and Pneumology of Quebec, Laval University, Quebec, Canada

²Centre Sherbrooke Molecular Imaging, Centre for Research Étienne-lebel, Centre Hospitalier Universitaire de Sherbrooke, Université de Sherbrooke, Sherbrooke, Canada

^*Corresponding Author(s): Jacques Couet, Groupe de Recherche en Valvulopathies, Centre de Recherche, Institut universitaire de cardiologie et de pneumologie de Québec 2725, Chemin Sainte-Foy, Quebec City, QC, G1V 4G5, Canada, Tel: 1-418-656-4760, Fax: 1-418-656-4509 Email: Marie Arsenault, MD, Group valvulopathies Research, Research Center, Institute of Cardiology and Pneumology of Quebec, Laval University, Quebec, Canada, Tel: 1-418-656-4760, Fax: 1-418-656-4509 Email: