Biochemistry & Pharmacology: Open Access

Biochemistry & Pharmacology: Open Access
Open Access

ISSN: 2167-0501

Research Article - (2015) Volume 4, Issue 4

Increasing Bioavailability of Cytotoxic Agents through Prolonged Therapy and Addition of Polymechanistic Antiangiogenic Agents Enhances Antitumor Response in Pancreatic Cancer

Awasthi N1,2*, Schwarz MA1,4, Wang C3, Williams SN3 and Schwarz RE1,2
1Department of Surgery, Indiana University School of Medicine, South Bend, IN 46617, USA
2Division of Surgical Oncology, Department of Surgery, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
3Department of Biochemistry, the University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
4Department of Pediatrics, Indiana University School of Medicine, South Bend, IN 46617, USA
*Corresponding Author: Awasthi N, Department of Surgery, Indiana University School of Medicine, 1234 Notre Dame Ave, South Bend, IN 46617, USA, Tel: 574-631-5780, Fax: 574-631-7821 Email:

Abstract