Increased Serum Tryptophan but not Kynurenine/Tryptophan Ratio is Associated with the Risk of Interferon-Alpha Associated Depression in Hepatitis C Virus Patients

Oxenkrug GF^1*, Turski WA², Zgrajka W³, Weinstock JV⁴, Ruthazer R⁵ and P Summergrad¹

¹Department of Psychiatry, Tufts Medical Center, Tufts University, Boston, MA, USA

²Department of Experimental and Clinical Pharmacology, Medical University of Lublin, Poland

³Department of Toxicology, Institute of Rural Health, Lublin, Poland

⁴Division of Gastroenterology/Hepatology, Tufts Medical Center, Tufts University, Boston, MA, USA

⁵Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Tufts University, Boston, MA, USA

^*Corresponding Author: Oxenkrug GF, Psychiatry and Inflammation Program, Menninger Department of Psychiatry and Behavioral Sciences and Michael E Debakey Va Medical Center,Department of Psychiatry, Tufts University, Tufts Medical Center, Boston, MA,02111, USA, Tel: (617) 636-5000 Email: