Improving Phosphopeptide/Protein Identification Using a New Data Mining Framework for MS/MS Spectra Preprocessing

Fabio R. Cerqueira^1*, Sandra Morandell², Stefan Ascher², Karl Mechtler³, Lukas A. Huber², Bernhard Pfeifer¹, Armin Graber⁴, Bernhard Tilg¹ and Christian Baumgartner^1*

¹Research Group for Clinical Bioinformatics, Institute of Biomedical Engineering, King Saud bin Abdulaziz University for Health Sciences, Medical Informatics and Technology, Eduard Wallnoefer Zentrum 1, 6060, Hall in Tirol, Austria

²Biocenter, Division of Cell Biology, Medical University of Innsbruck, Fritz-Pregl Str. 3, 6020, Innsbruck, Austria

³Research Institute of Molecular Pathology (IMP), Dr Bohr-Gasse 7 and Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Dr Bohr Gasse 3, A1030 Vienna, Austria

⁴Institute for Bioinformatics, University for Health Sciences, Medical Informatics and Technology, Eduard Wallnoefer Zentrum 1, 6060, Hall in Tirol, Austria

^*Corresponding Author(s): Fabio R. Cerqueira, Research Group for Clinical Bioinformatics, Institute of Biomedical Engineering, University for Health Sciences, Medical Informatics And Technology, Eduard Wallnoefer Zentrum 1, 6060, Hall In Tirol, Austria, Tel: +43 50 8648 3827, Fax: +43 50 8648 673827 Christian Baumgartner, Research Group for Clinical Bioinformatics, Institute of Biomedical Engineering, University for Health Sciences, Medical Informatics And Technology, Eduard Wallnoefer Zentrum 1, 6060, Hall In Tirol, Austria