Impacted Cera Septal Occluder Device in Right Ventricular Outflow
Journal of Perioperative Medicine

Journal of Perioperative Medicine
Open Access

ISSN: 2684-1290

+44 7868 792050

Case Report - (2018) Volume 1, Issue 1

Impacted Cera Septal Occluder Device in Right Ventricular Outflow Tract (RVOT): A Potential Challenge for the Anesthesiologist

Indira Malik1*, Tanunita M1, Soumyadip S2, Saket A2 and Tomar AS1
1Department of Anesthesiology and Critical Care, Govind Ballabh Pant Institute of Postgraduate Medical Education and Research (GIPMER), New Delhi, India
2Department of Cardiothoracic and Vascular surgery, Govind Ballabh Pant Institute of Postgraduate Medical Education and Research (GIPMER), New Delhi, India
*Corresponding Author: Indira Malik, Department of Anesthesiology and Critical Care, Govind Ballabh Pant Institute of Postgraduate Medical Education and Research (GIPMER), New Delhi, India, Tel: 9350224435 Email:


Atrial septal defects are amenable to management by surgical and transcatheter device (TC) closure. Though, TC closure has several advantages it is fraught with many complications, such as device embolization (DE), arrhythmias and thrombus formation to name a few. DE is uncommon in experienced hands, but it can occur right from the immediate post-procedure period to after a few months or even years. DE has been reported from a multitude of locations and retrieval is possible percutaneously in majority of cases. However, there are instances where an embolized device may result in potentially life threatening complications, thus necessitating surgical intervention and pose a challenging scenario for the anaesthesiologist.

Keywords: Atrial septal defect; Transcatheter closure; Device embolization

Case Report

Ostium secundum atrial septal defects (OS- ASDs) are one of the commonest congenital heart defects (CHD); with an estimated prevalence of 75/100,000 live births [1]. In 1976, the first transcatheter (TC) closure of ASD, using a double umbrella device in human beings was reported [2].

Although it is a simple procedure and avoids the need for cardiopulmonary bypass (CPB), it has its share of complications; device embolization (DE) being the commonest reason for emergent surgical intervention which often presents a challenge for the anaesthesiologist [1].

Here, we report the case of a patient who underwent successful surgical retrieval of an ASD occluder device embolized to the right ventricular outflow tract (RVOT) four months after placement. A 9-years-old girl was diagnosed as a case of OS ASD (28 mm) with left to right (L→R) shunt and underwent ASD closure with Cera ASD occluder (LT-ASD-30). After the procedure, chest infections subsided but palpitation persisted; transthoracic echocardiography (TTE) revealed that the device had embolized to the RVOT which was confirmed in right ventricle (RV) angiogram. Fluoroscopy guided retrieval with 20 mm snare was unsuccessfully attempted. She was asymptomatic and haemodynamically stable; physical examination revealed no abnormal findings. Since the device seemed impacted and risk of RVOT obstruction or perforation was significant, she was referred to cardiothoracic operating room (CTVS OR) for further management.

Standard ASA monitors were attached; a 16 G IV line and arterial line were secured under local anaesthesia. General anaesthesia (GA) was induced with fentanyl (5 μg/kg), thiopentone (2 mg/kg) and pancuronium (0.1 mg/kg) for endotracheal intubation. A central venous line was placed in right internal jugular vein (IJV). Anaesthesia was maintained with fentanyl, pancuronium, midazolam and sevoflurane; haemodynamic parameters remained stable. CPB with moderate hypothermia was instituted after systemic heparinisation. The device was found impacted in RVOT with partial fibrosis around it and retrieved safely. ASD was closed with pericardial patch and the patient weaned off CPB with nitroglycerine (1 μg/kg/min) and adrenaline infusion (0.04 μg/kg/min). After reversal of anticoagulation and securing haemostasis, the patient was shifted to intensive care unit (ICU) for elective mechanical ventilation. The postoperative course was uneventful and she was discharged with full recovery on the 6th day (Figures 1 and 2).


Figure 1: RV Angiogram showing device obstructing RVOT.


Figure 2: Intraoperative image: Removal of the device.


Transcatheter closure of ASDs has gained popularity due to a short learning curve, cosmetic benefits, avoidance of complications of CPB, reduced morbidity and hospital stay [3]. Rapid progress has followed the development of Dacron covered stainless steel devices and expert use of echocardiography for septal assessment, sizing and postprocedural evaluation.

Percutaneous ASD closure is possible in isolated OS-ASD, normal pulmonary venous drainage, L→R shunt 1.5:1, maximum size <35 mm in any plane and adequate rims [4].

A series of 417 patients reported 8.65% complications [3]. Major complications are DE (0.01-0.55% in expert hands), arrhythmias, most commonly atrial fibrillation, thrombosis (1.2%), cardiac erosion (0.1%- 0.3%), pericardial effusion, transient heart block and sepsis (0.8%) [5,6].

Common reasons for DE are very large defect, undersized device, small left atrium (LA) to accommodate the device, inadequate or floppy rim and opera-tor inexperience [7]. DE can occur within the first few days as well as few years after the intervention, since endothelialisation may not be complete and predisposing factors like infections, may favor thrombus formation and embolization, even months after the procedure [8].

Percutaneous retrieval is successful in 50-75% cases, pulmonary artery and aorta being the easiest sites from which to retrieve. Another database reported 77.2% cases of surgical retrieval and 16.7% by percutaneous technique [9,10].

DE can precipitate potentially life threatening complications like arrhythmias, hypotension and hypoxia due to flow obstruction in the left ventricular outflow tract or RVOT leading to an extremely challenging scenario for the anaesthesiologist, should these patients land up in the OR following a failed percutaneous retrieval attempt.

Guarded premedication, wide bore I/V and arterial access, opioid based induction technique, availability of inotropic support, blood and blood products, in the event of haemodynamic collapse, should be ensured.


Postoperatively, a joint decision with the surgical team should be taken regarding early versus delayed extubation. In our case, though the device was lodged in RVOT, patient remained asymptomatic, probably because fibrosis rendered the device immobile and prevented dynamic RVOT obstruction.


  1. Chessa M, Carminati M, Butera G, Bini RM, Drago M, et al. (2002) Early and late complications associated with transcatheter occlusion of secundum atrial septal defect. J Am Coll Cardiol 39: 1061-1065.
  2. King TD, Thompson SL, Steiner C (1976) Secundum atrial septal defect. Nonoperative closure during cardiac catheterization. JAMA 235: 2506-2509.
  3. Raghuram AR, Krishnan R, Kumar S (2008) Complications in atrial septal defect device closure. Interact Cardiovasc Thorac Surg 7: 167-169.
  4. Misra M, Sadiq A, Namboodiri N (2007) The ‘aortic rim’ recount: Embolization of interatrial septal occluder into the main pulmonary artery bifurcation after atrial septal defect closure. Interact Cardiovasc Thorac Surg 6: 384-386.
  5. Tadros VX, Asgar AW (2016) Transcatheter closure of atrial septal defects: An update on ASD occlusion devices. Cardiac Interventions Today 10: 56-60.
  6. Levi DS, Moore JW (2004) Embolization and retrieval of the amplatzer septal occluder. Cathet Cardiovasc Intervent 61: 543-547.
  7. Celik T, Ozturk C, Bozlar U (2016) Late embolization of the atrial septal occluder device into the abdominal aorta. Indian Heart J 68: 200-201.
  8. Lysitsas DN, Wrigley B, Banerjee P, Shiu MF, Been M, et al. (2009) Presentation of an embolised amplatzer septal occluder to the main pulmonary artery 2 years after implantation. Int J Cardiol 131: 106-107.
  9. Saritas T, Yucel IK, Demir IH (2016) Comparison of transcatheter atrial septal defect closure in children, adolescents and adults: Differences, challenges and short-, mid- and long-term results. Korean Circ J 46: 851-861.
  10. Das S, Kumar P, Bhardwaj V (2016) Anesthetic management of Amplatzer atrial septal defect closure device embolization to right ventricular outflow tract. Saudi J Anaesth 10: 335-338.
Citation: Indira M, Tanunita M, Soumyadip S, Saket A, Tomar AS (2017) Impacted Cera Septal Occluder Device in Right Ventricular Outflow Tract (RVOT): A Potential Challenge for the Anesthesiologist . J Perioper Med 1: 103.

Copyright: © 2017 Indira M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.