Endocrinology & Metabolic Syndrome
Open Access

Human Growth Hormone and Treatment for Hormonal Imbalance

Ryo Matsuura^{* *}Correspondence: Ryo Matsuura, Department of Endocrinology, Missouri State University, Springfield, USA, Email:

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Description

Human growth hormone study dates back a little more than a century. Growth hormone, which was first shown to have a profound impact on longitudinal growth, is now understood to have broader impacts on the metabolism of proteins, lipids, and carbohydrates. Growth hormone is anticipated to play additional roles in human physiology, including those related to sleep and reproduction. Furthermore, there is some evidence to suggest that growth hormone may possibly play a role in the control of immunological response, mental health, and ageing. Human growth hormone is now widely available and safe for use in humans thanks to recombinant DNA technology, but its pharmacological qualities are poor.

However, rather than a primary defect in growth hormone synthesis, most growth hormone-deficient people show a secretory defect, and advances in our knowledge of the neuroendocrine regulation of growth hormone secretion have established the rationale for the use of drugs to stimulate the release of endogenously synthesized growth hormone. This is going to be a significant area for developing drugs in the future. Hormonal imbalances arise when there is too much or too little secretion of a hormone in the bloodstream. Because of their vital role in the body, even small hormonal imbalances can cause side effects all over the body.

Both females and males can be affected by imbalances in insulin, growth hormones, steroids, and adrenaline. Females may also experience imbalances in progesterone and estrogen levels, while males are more likely to experience imbalances in testosterone levels. When the endocrine system is not working properly, it leads to hormonal imbalance. Endocrine glands are specific cells that produce, store, and discharge hormones into the bloodstream. There are various endocrine glands that are located throughout the body that control different organs, including the

• Gonads (testis and ovaries).

• Adrenal glands

• pituitary gland

• pineal gland

• The thyroid and parathyroid glands

• hypothalamus gland

• pancreatic islets

Several medical circumstances can affect the endocrine glands. Certain environmental factors and lifestyle habits can also play a role in hormonal imbalances.

Treatment for hormonal imbalance

Hormones or birth control: For those who are suffering with infertility, medications that contain progesterone and estrogens can help to regulate irregular menstrual cycles and symptoms. Birth control is available as a ring, patch, pill, shot, or Intrauterine Device (IUD).

Vaginal estrogen: People suffering with vaginal dryness associated with changes in oestrogen levels can use creams that contain estrogen directly on vaginal tissues to reduce symptoms. They can also use estrogen rings and tablets to get rid of vaginal dryness.

Hormone replacement medications: Medications are available to reduce severe symptoms associated with menopause, such as night sweats or hot flashes.

Eflornithine (Vaniqa): This prescription cream may be used to reduce excessive facial hair growth in women.

Anti-androgen medications: Medicines that block the predominately male-sex hormone androgen can help to limit severe acne and excessive hair growth or hair loss.

Clomiphene (Clomid) and letrozole (Femara): These medicines help to stimulate ovulation in people suffering with PCOS and who are trying to become pregnant. Physicians may also give gonadotropin injections to people with PCOS and infertility to increase the chances of pregnancy.

Assisted reproductive technology: In-Vitro Fertilization (IVF) can be used to help women with complications of PCOS.