Endocrine-Mediated Effects of a Benzophenone-Related Chemical, 2,3,4,4’-Tetrahydroxybenzophenone, Based on Uterotrophic Assay, Hershberger Assay, and Subacute Oral Toxicity Study

Kanji Yamasaki^1*, Hirokazu Okuda² and Haruhiko Kikkawa¹

¹Chemicals Evaluation and Research Institute, Tokyo, Japan

²Japan Bioassay Research Center, Kanagawa, Japan

^*Corresponding Author: Kanji Yamasaki, Chemicals Evaluation and Research Institute, 1-4-25 Kouraku, Bunkyo-ku, Tokyo 112-0004, Japan, Tel: +81-3-5804-6136, Fax: +81-3-5804-6149 Email:

Keywords: 2,3,4,4’-tetrahydroxybenzophenone; Uterotrophic assay; Hershberger assay; Test guideline 407; Rat; Endocrine effects

Introduction