Effects of Intracoronary Collagenase Injection in a Porcine Model: A Safety Dose-Finding Study

Azriel B Osherov^1,4, Sang Yup Lim^1,3, Jagdish Butany², Beiping Qiang¹, Ronen Jaffe^1,5, Ilana Erlich¹ and Bradley H Strauss^1,2*

¹Schulich Heart Centre, Sunnybrook Health Sciences Centre, Canada

²University Health Network, Toronto, Canada

³Korea University Ansan Hospital, Ansan, Korea

⁴Barzilai Medical Centre, Ben-Gurion University, Ashkelon, Israel

⁵Lady Davis Carmel Medical Centre, Technion-Israel Institute of Technology, Haifa, Israel

^*Corresponding Author: Bradley H Strauss, Reichmann Chair in Cardiovascular Sciences, Schulich Heart Centre, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, D4-06, Toronto, Ontario, M4N 3M5, Canada, Tel: 4164806066, Fax: 4164806174 Email: