Effects of Hyperosmotic Sodium Chloride Perfusion on Ischemia/Reperfusion Injury in Isolated Hearts of Normal and Stroke-Prone Spontaneously Hypertensive Rats

Wei-Li Shen^1#, Li-Bing Chen^2#, Jian-Xing Zhao¹, Shu-Jie Guo¹, Yi-Chen Chen¹, Li-Ping Wang¹, Yong Cao³, Wen-Jun Yuan⁴ and Hong Chen^1*

¹Department of Pharmacology and Shanghai Key Laboratory of Vascular Biology, Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China

²Department of Thoracic Surgery, 85 Hospital, Shanghai 200052, China

³Department of Thoracic Surgery, 6^th Ren Ming Hospital, Shanghai Jiao Tong University, Shanghai 200233, China

⁴Department of Physiology, Ningxia Medical University, Yinchuan 750004, PR China

^#Contributed equally to this work

^*Corresponding Author: Hong Chen, M.D., PhD, Department of Pharmacology, Shanghai Jiaotong University School of Medicine, 280 South Chong Qing Road, Shanghai 200025, China, Tel: 62800084, Fax: +86-21-62800084 Email: