Effects of Atmospheric Particles and Several Model Particles of Particulate Matter Components on Human Monocyte-Derived Macrophage Oxidative Responses

Masayuki Ohyama^1*, Susumu Akasaka², Toru Otake³, Kenji Morinaga⁴, Young Whan Kim⁵, Kyong-Whan Moon⁵, Takayuki Kameda⁶ and Shuichi Adachi⁷

¹Department of Environmental Health, Osaka Prefectural Institute of Public Health, Osaka, Japan

²Department of Planning and Coordination, Osaka Prefectural Institute of Public Health, Osaka, Japan

³Department of Virology, Osaka Prefectural Institute of Public Health, Osaka, Japan

⁴Department of Work Environment Research Group, Japanese National Institute of Occupational Safety and Health, Kawasaki, Japan

⁵Department of Environmental Health, Korea University, Seoul, Korea

⁶Department of Institute of Medical, Pharmaceutical and Health Sciences, Faculty of Pharmacy, Kanazawa University, Kanazawa, Japan

⁷Department of Public Health, Sagami Women’s University, Sagamihara, Japan

^*Corresponding Author: Masayuki Ohyama, Department of Environmental Health, Osaka Prefectural Institute of Public Health, 1-3-69, Nakamichi, Higashinariku, Osaka 537-0025, Japan, Tel: 81 66 972 1321, Fax: 81 66 9722 393 Email:

Keywords: Particulate matter, Diesel exhaust particles, 3-Nitrobenzanthrone, Superoxide, Hydroxyl radical, Macrophage

Abbreviations